Phases, active trials: Phase 1: 12, Phase 1/2: 14, Phase 2: 38, Phase 2/3: 3, Phase 3: 55, Phase 4: 13, No phase listed: 43
Sanofi and Regeneron operate an extensive co-development partnership spanning immunology, oncology, and rare disease. Dupixent (dupilumab), the IL-4Rα-blocking antibody, is the fastest-growing biologic in history, and Sanofi continues expanding its label into new type-2 inflammatory conditions (COPD, prurigo nodularis, alopecia areata). Their shared oncology pipeline includes cemiplimab (Libtayo), the PD-1 inhibitor with approvals in skin cancers and NSCLC, plus a broad REGN antibody program in hematology and solid tumors. Sanofi's rare disease heritage (Gaucher, Pompe, Fabry) continues with next-generation enzyme replacement therapies and gene therapies.
- Type-2 inflammation / allergy (IL-4Rα, IL-33, TSLP)
- Oncology (PD-1, bispecifics, hematology)
- Rare / metabolic disease (lysosomal storage, hemophilia)
- Neurology
- Vaccines (Beyfortus RSV)
- Dupixent (dupilumab): IL-4Rα, atopic dermatitis/asthma/COPD
- Libtayo (cemiplimab): PD-1, skin cancers/NSCLC
- Sarclisa (isatuximab): anti-CD38, multiple myeloma
- Zynquista (sotagliflozin): SGLT1/2, T1D/heart failure
- REGN5458: BCMAxCD3 bispecific, myeloma
- Fitusiran: RNAi-based hemophilia therapy
A primary completion date pushed out, enrollment cut, or a primary endpoint changed in the last 90 days. Active trials only.
| Trial | Warning signs | Status |
|---|---|---|
| Avalglucosidase Alfa French Post-trial Access for Participants With Pompe… NCT05164055 | Primary completion moved 9 months later | Active, Not Recruiting |
10 more on the Trials at Risk page. See which trials →
Phase 2 and Phase 3 trials with a primary completion date in the next 180 days, as ClinicalTrials.gov estimates it today. Active trials only.
| Trial | Scheduled | Phase |
|---|---|---|
| Rilzabrutinib for the Adult Participants With Chronic ITP Who Have Completed… NCT07216079 | Nov 25, 2026 · Estimated | Phase 3 |
19 more on the Completions page. See the calendar →
Monitor the Sanofi / Regeneron pipeline daily
Get a daily digest when Sanofi / Regeneron registers new trials or updates existing protocols. Free plan, no credit card required.
Start monitoring free| Condition / indication | Active trials |
|---|---|
| Healthy Volunteers | 17 |
| Atopic Dermatitis | 8 |
| Dermatitis Atopic | 8 |
| Multiple Sclerosis | 6 |
| Asthma | 5 |
| Chronic Graft Versus Host Disease | 5 |
| Pneumococcal Immunization | 5 |
| Type 1 Diabetes | 5 |
Dupixent's label expansion program generates consistent new trial registrations across type-2 inflammatory conditions. Any company developing IL-4, IL-13, IL-33, or TSLP-targeted therapies needs to monitor Sanofi/Regeneron's trial activity closely.
DataLookout monitors ClinicalTrials.gov daily and surfaces changes to Sanofi / Regeneron's registered studies: new trial registrations, status transitions (for example "Not yet recruiting" to "Recruiting"), site additions, and protocol amendments. This is the intelligence layer that bridges the gap between quarterly investor calls and day-to-day pipeline developments.
- Sponsor normalization: Sanofi / Regeneron may register trials under multiple legal entity names. DataLookout normalizes all related entities to a single canonical sponsor for complete pipeline coverage.
- Daily updates: ClinicalTrials.gov is queried each morning. New registrations and updates appear in that day's digest.
- Field-level change detection: Status changes, enrollment updates, and site additions are detected and surfaced, not just new registrations.
- Phase filtering: Focus on Phase 3 pivotal trials, Phase 2 proof-of-concept studies, or all phases for comprehensive coverage.
- Indication filtering: Combine sponsor monitoring with indication keywords to focus on the therapeutic areas relevant to your business.
Automate your Sanofi / Regeneron pipeline intelligence
Used by pharma BD, strategy, and competitive intelligence professionals. Setup takes under 5 minutes.
Get started free| Trial | Status | Latest tracked change | Seen |
|---|---|---|---|
| Study of a Combination SARS-CoV-2 Recombinant Spike and High-Dose Inactivated… NCT07890454 | Recruiting | Start date changed from estimate of Nov 9, 2026 to Oct 28, 2026 | 2026-11-14 |
| Study of Different Formulations of Vaccines Encoding the RSV Monovalent Antigen… NCT07516418 | Active, Not Recruiting | Final enrollment: 360 participants (planned 570) | 2026-11-14 |
| A Study to Investigate the Efficacy and Safety of SAR444336 in Adults With… NCT07156175 | Active, Not Recruiting | Final enrollment: 60 participants (planned 54) | 2026-11-13 |
| Study to Evaluate the Efficacy and Safety of Oral Rilzabrutinib in Adults With… NCT07007962 | Recruiting | Trial sites expanded: 36 → 54 locations | 2026-11-13 |
| Study of a Recombinant Spike COVID-19 Vaccine With Matrix-M in Older Adults and… NCT07861542 | Active, Not Recruiting | Enrollment closed, study ongoing | 2026-11-13 |
Each trial page shows every change DataLookout has recorded for that trial.