Data as of 2026-09-16.
Lung cancer splits into two clinically distinct histologies. Non-small cell lung cancer (NSCLC) accounts for the large majority of trials and is increasingly segmented by molecular driver — EGFR, KRAS G12C, HER2, ALK, ROS1, BRAF, and RET — each with its own targeted-therapy program. Small cell lung cancer (SCLC) is a separate, faster-growing histology with a distinct trial set. A useful lung-cancer competitive picture has to track both the histology split and the molecular-subtype races at once.
Molecular-driver subtypes are subsets of NSCLC and overlap each other, so the rows below do not sum to the total above — each links to a dedicated biomarker landscape. KRAS G12C spans lung, colorectal, and pancreatic cancer; its page covers all indications.
By histology
| Subtype | Active | Recruiting | Phase 3 |
|---|---|---|---|
| Non-Small Cell Lung Cancer (NSCLC) | 2425 | 1285 | 336 |
| Small Cell Lung Cancer (SCLC) | 479 | 257 | 64 |
By molecular driver (within NSCLC)
| Subtype | Active | Recruiting | Phase 3 |
|---|---|---|---|
| EGFR-mutant | 396 | 194 | 66 |
| KRAS G12C | 70 | 32 | 16 |
| HER2-mutant | 84 | 49 | 8 |
| ALK-positive | 73 | 28 | 9 |
| ROS1 fusion | 37 | 19 | 6 |
| BRAF V600E | 10 | 4 | 1 |
| RET fusion | 8 | 2 | 2 |
Track every new lung cancer trial automatically
ClinicalTrials.gov updates daily. Our pipeline monitors it for you and delivers a clean digest every morning.
Get the free digest, no credit cardLargest industry-sponsored lung cancer trial portfolios by active study count:
| Industry sponsor | Active trials |
|---|---|
| AstraZeneca | 100 |
| Merck (MSD) | 36 |
| Pfizer | 33 |
| Sichuan Baili Pharmaceutical Co., Ltd. | 29 |
| Bristol-Myers Squibb | 27 |
Our pipeline pulls from ClinicalTrials.gov every day. For a lung cancer watchlist or saved search, your digest covers:
- New study registrations and status changes (for example opened to recruiting, completed)
- Protocol changes: enrollment, endpoints, phase, and completion-date movements
- New sponsor entrants into a subtype
- Phase filters (Phase 1 for novel mechanisms, Phase 3 for registration programs)
- Sponsor-type filters (large pharma vs. emerging biotech vs. academic)
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DataLookout checks ClinicalTrials.gov every day and records what changed on each trial: status, enrollment, phase, primary endpoint, completion dates, sites, sponsor, and the stated reason a trial stopped. Add a sponsor or a disease to your watchlist, or save any search, and the changes arrive in a daily or weekly email digest.
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Data as of 2026-09-16, from ClinicalTrials.gov. View the full pipeline on the dashboard.